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Journal Publications

  1. Cardaci TD, VanderVeen BN, Bullard BM, McDonald SJ, Unger CA, Enos RT, Fan D, Velázquez KT, Frizzell N, Spangenburg EE, Murphy AE. Obesity worsens mitochondrial quality control and does not protect against skeletal muscle wasting in murine cancer cachexia. Journal of Cachexia, Sarcopenia, and Muscle. 2024 Feb;15(1):124-137.

  2. Unger CA, Hope MC III, Aladhami AK, Cotham WE, Socia CE, Rice BC, Clegg DJ, Velázquez KT, LaVoie HA, Hollis F, Enos RT. A novel tissue-specific insight into sex steroid fluctuations throughout the murine estrous cycle. Endocribology, 2024,165, 1-13. 

  3. Cunningham P, Unger CA, Patton EA, Aiken A, Browne A, James E, Aladhami AK, Hope MC, VanderVeen BN, Cardaci TD, Murphy EA, Enos RT, Velázquez KT. Platelet status in cancer cachexia progression in ApcMin/+ mice. Frontiers in Immunology. 2023

  4. Unger CA, Aladhami AK, Hope MC, Cotham WE, Nettles KW, Clegg DJ, Velázquez KT, Enos RT. Skeletal muscle endogenous production ameliorates the metabolic consequences of a high-fat diet in male mice. Endocrinology. 2023 Jun 26;164(8):bquac105. 

  5. Patton EA, Cunningham P, Noneman M, Helms H, Martinez-Muniz G, Sumal AS, Dhameja MK, Unger CA, Aladhami AK, Enos RT, Chatzistamou I, Velázquez KT.  Acute dministration of Ojeok-san ameliorates pain-like behaviors in pre-clinical models of inflammatory bowel diseases. Nutrients 2023, March 23, 15(7), 1559.  

  6. VanderVeen BN, Cardaci TD, Cunningham P, McDonald SJ, Bullard BM, Fan D, Murphy EA, Velázquez KT (2022). Quercetin improved muscle mass and mitochondrial contant in a murine model of cancer and chemotherapy-induced cachexia. Nutrients. 2022 Dec 25;15(1):102 

  7. Unger C, Hope III MC, Aladhami A, Velázquez KT, Enos RT.  How stable is your vivarium’s temperature? Fluctuations in vivarium temperature significantly impact metabolism and behavior impeding reproducibility. AJP

  8. Unger C, Aladhami A, Hope III MC, Pourhoseini S, NagarkattiM, McGuinness OP, Murphy EA,  Velázquez KT, Enos RT (2022). Congenital adiponectin deficiency mitigates high-fat-diet-induced obesity in gonadally intact male and female, but not in ovariectomized mice. Sci Rep 2022 Oct 5;12(1):16668. 

  9. McDonald S, Cranford T, VanderVeen B, Cardaci T,  Velázquez KT, Enos RT, Chatzistamou I, Fan D, Murphy EA. Mir155 deficiency reduces breast tumor burden in the MMTV-PyMT mouse model. Physiol Genomics. 2022 Nov 1;54(11):433-422.

  10. Aladhami AK, Unger C, Hope III MC, Cotham WE, Velázquez KT, Enos RT (2022).  Augmenting skeletal muscle estrogen does not prevent or rescue obesity-linked metabolic impairments in female mice. Endocrinology.  2022 Oct 11;163(11):bquac146

  11. VanderVeen BN, Cardaci TD, McDonald SJ, Madero SS, Unger CA, Bullard BM, Enos RT, Velázquez KT, Fan D, Murphy EA (2022). Obesity reduced survival with 5-Fluorouracil and did not protect against chemotherapy-induced cachexia or immune clee cytotoxicity in mice. Cancer Biology & Therapy

  12. Cunningham P, Patton E, VanderVeen BN, Unger C, Aladhami, A Enos RT, Madero S,  Chatzistamou I, Fan D, Murphy EA, Velázquez KT (2022). Sub-chronic oral toxicity screening of quercetin in mice. BMC Complemen Med Ther. 2022 Oct 23;22(1):279

  13. Cunningham P, Sumal A, Patton E, Helms Henry, Noneman MT, Martinez-Muniz Gustavo, Bader JE, Chatzistamou I, Aladhami AK, Unger C, Enos RT, Shin HS, Velázquez KT (2022). Ojeok-san ameliorates visceral and somatic nociception in a mouse model of colitis induced colorectal cancer. PlosOne 2022:17(6):e0270338.

  14. McDonald SJ, VanderVeen BN, Velázquez KT, Enos RT, Fairman CM, Cardaci TD, Fan D, Murphy EA (2022). Therapeutic potential of emodin for gastrointestinal cancers. Integr Cancer Ther. 2022 Jan-Dec;21:15347354211067469

  15. Aladhami A, Unger C, Ennis S, Altomare D, Ji H, Hope M, Velázquez KT, Enos RT. (2021) Macrophage tumor necrosis factor-alpha deletion does not protect against obesity-associated metabolic dysfunction. FASEB

  16. Sougiannis AT, Enos RT, VanderVeen BN, Velázquez KT, Kelly B, McDonald S, Cotham W, Chatzistamou I, Nagarkatti M, Fan D, and EA Murphy (2021). Safety of natural anthraquinone emodin: as an assessment in mice. BMC Pharmacol Toxicol. Jan 28;22(1):9 3.

  17. VanderVeen BN, Sougiannis AT, Velázquez KT, Cason JA, Fan D, Murphy EA. (2020) The effects of 5-FU on skeletal muscle resident and infiltrating immune cells in mice. Front Physiol. 2020 Dec7; 11:593468. 4.

  18. Bader JE, Carson MS, Enos RT, Velázquez KT, Sougiannis AT, Singh UP, Becker WJ, Nagarkatti M, Fan D, Murphy EA. (2020) High fat diet fed ovariectomized mice are susceptible to accelerated subcutaneous tumor growth potentially through adiposity, adipose inflammation, and local insulin-like growth factor release. Oncotarget. Dec 8;11(49):4554-4569.

  19. Sougiannis AT, VanderVeen BN, Cranford TL, Enos RT, Velázquez KT, McDonald S, Bader JE, Chatzistamou I, Fan D, and EA Murphy (2020). Impact of weight loss and partial weight regain on immune cell and inflammatory markers in adipose tissue in male mice. J Appl Physiol. Oct 1:129(4):909-919. 6.

  20. Velázquez KT, Enos RT, Bader JE, Sougiannis A, Carson MS, Chatzistamou I, Carson JA, Nagarkatti PS, Nagarkatti M, Murphy EA. (2019) Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice. World Journal of Hepatology. Aug27;11(8):619-637.

  21. Sougiannis AT, VanderVeen BN, Enos RT, Velázquez KT, Bader JE, Carson MS, Chatzistamou I, Walla M, Pena MM, Kubinak JL, Nagarkatti M, Carson JA, and EA Murphy (2019).  Impact of 5 Fluoracil Chemotherapy on Gut Inflammation, Functional Parameters, and Gut Microbiota.  Brain Behav Immun. Feb 23. pii: S0889-1591(18)31227-3. doi: 10.1016/j.bbi.2019.02.020. [Epub ahead of print]

  22. Bader JE, Enos RT, Velázquez KT, Carson MS, Sougiannis A, McGuinness OP, Robinson CM, Murphy EA. Clodronate-Liposome treatment results in neutrophilia, anemia, and is not effective in limiting obesity-linked metabolic impairments.  Am J Physiol Endocrinol Metab. 2018Dec 21

  23. Cranford TL, Velázquez KT, Enos RT, Sougiannis AT, Bader JE, Carson MS, Bellone RR, Chatzistamou I, Nagarkatti M, Murphy EA. Effects of high fat diet –induced obesity on mammary tumorigenesis in the PyMT/MMTV murine model. Cancer Biology Therapy. 2018 Nov 2:1-10. Epub ahead of print

  24. Fix DK, Hardee JP, Gao S, VanderVeen BN, Velázquez KT, Carson JA. The role of gp130 in basal and exercise trained skeletal muscle mitochondrial quality control. J Appl Physiol. 2018. Feb 1

  25. Bader JE, Enos RT, Velázquez KT, Carson MS, Nagarkatti PS, Chatzistamou I, Davis JM, Robinson C, Murphy EA. Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer. Am J Physiolo Gastrointest Liver Physiol 2018. Jan 1;314(1):G22-G31

  26. Mehrpouya-Bahrami P, Chitrala KN, Ganewatta MS, Tang C, Murphy EA, Enos RT, Velázquez KT, McClellan J, Nagarkatti M, Nagarkatti P. Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet induced obesity. Sci Rep. 2017 Nov 15(7):15645

  27. Velázquez KT, Enos RT, Carson MS, Cranford TL, Bader JE, Sougiannis AT, Prichett C, Fan D, Carson JA, Murphy EA. Mir155 deficiency aggravates high-fat-diet-induced adipose tissue fibrosis in male mice. Physiol Rep. 2017. Sep;5(18).

  28. Cranford TL, Velázquez KT, Enos RT, Bader JE, Carson MS, Chatzistamou I, Nagarkatti M, Murphy EA. Loss of monocyte chemoattractant protein-1 expression delays mammary tumorigenesis and reduces localized inflammation in the C3(1)/SV40Tag triple in triple negative breast cancer murine model. Cancer Biology Therapy. 2017 Feb;18(2):85-93.

  29. Enos RT Velázquez KT, Carson MS, McClellan JL, Nagarkatti PS, Nagarkatti M, Davis JM, Murphy EA. A low dose of dietary quercetin fails to protect against the development of an obese phenotype in mice. PLoS One.  2016 Dec 13;11(12):e0167979

  30. Velázquez KT, Enos RT, Carson MS, Cranford TL, Bader J, Chatzistamou I, Singh U, Nagarkatti PS, Nagarkatti M, Davis JM, Carson JA, Murphy EA. Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model. Am J Physiolo Gastrointest Liver Physiol. 2016 Sept 8.

  31. Enos RT, Velázquez KT, McClellan JL, Cranford TL, Nagarkatti PS, Nagarkatti M, Davis JM, Murphy EA. High-fat diets rich in saturated fat protect against azoxymethane/dextran sulfate sodium-induced colon cancer. Am J Physiolo Gastrointest Liver Physiol. 2016 Jum 1;310(11):G906-19.

  32. Velázquez KT, Enos RT, McClellan JL, Cranford TL, Chatzistamou I, Singh UP, Nagarkatti M, Nagarkatti PS, Fan D, Murphy EA. MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate model of colon cancer. Am J Physiolo Gastrointest Liver Physiol. 2016 Mar 15;310(6):G347-58.

  33. Cranford TL, Enos RT, Velázquez KT, McClellan JL, Davis JM, Singh UP, Nagarkatti M, Nagarkatti PS, Robinson CM, Murphy EA. Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain. Int J Obes (Lond). 2016 May;40(5):844-51.

  34. Murphy EA, Velázquez KT, Herbert KM. Influence of high-fat diet on gut microbiota: a driving force for chronic disease risk. Curr Opin Clin Nutr Metab Care. 2015 Sep;18(5):515-20.

  35. Enos RT, Velázquez KT, McClellan JL, Cranford TL, Walla MD, Murphy EA. Lowering the dietary omega-6:omega-3 does not hinder nonalcoholic fatty liver disease development in a murine model. Nutr Res. 2015 May;35(5):449-59.

  36. Murphy EA, Enos R, Velázquez KT. Influence of exercise on inflammation in cancer: direct effect or innocent bystander? Exerc Sport Sci Rev. 2015 Jul;43(3):134-42.

  37. Smith SN, Paige C, Velázquez KT, Smith TP, Raja SN, Wilson SP, Sweitzer SM. Injury-specific promoters enhance herpes simplex virus-mediated gene therapy for treating neuropathic pain in rodents. J. Pain. 2015 Mar;16(3):283-90.    

  38. Velázquez KT, Enos RT, Narsale AA, Puppa MJ, Davis JM, Murphy EA, Carson JA. Quercetin supplementation attenuates the progression of cancer cachexia in the ApcMin/+ mouse. Journal of Nutrition. 2014 Jun;144(6):868-75.

  39. Enos RT, Velázquez KT, McClellan, Cranford TL, Walla MD, Murphy EA. Reducing the Dietary Omega-6:Omega-3 Utilizing α-Linolenic Acid; Not a Sufficient Therapy for Attenuating High-Fat-Diet-Induced Obesity Development Nor Related Detrimental Metabolic and Adipose Tissue Inflammatory Outcomes. PLOS One. 2014 Apr:9(4):e94897

  40. Enos RT, Velázquez KT, Murphy EA. Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases. The Journal of Nutritional Biochemistry. 2014 Jun;25(6):600-12

  41. Day ST, Enos RT, McClellan JL, Steiner JL, Velázquez KT, Murphy EA. Linking Inflammation to tumorigenesis in a Mouse Model of High-Fat-Diet-Enhance Colon Cancer. Cytokine. 2013 Oct;64(1):454-62.

  42. Enos RT, Davis JM, Velázquez KT, Day S, McClellan J, Murphy EA. Influence of Saturated Fat on Adiposity, Macrophage Behavior, Inflammation, and Metabolism: Composition Matters. J Lipid Res. 2013 Jan;54(1):152-63.

  43. Puppa MJ, White JP, Velázquez KT, Baltgalvis KA, Sato S. Baynes JW, Carson JA. The effect of exercise on IL-6-induced cachexia in the Apc (Min/+) mouse. J Cachexia Sarcopenia Muscle. 2012 3(2):117-37 Epub 2011 Nov 30.

  44. Velázquez KT, Mohammad HK, Sweitzer SM. Protein kinase C in pain: involvement of multiple isoforms. Pharmacol Res. 2007 Jun;55(6):578-89.

  45. Rivera-Arce JC, Morales-Crespo L, Vargas-Pinto N, Velázquez KT, Jorge JC. Central effects of the anabolic steroid17a-methyltestosterone in female anxiety. Pharmacology, Biochemistry and Behavior. 2006 Jun;84(2):275-81

  46. Jorge JC, Velázquez KT, Ramos DL, Lorenzini I, Marrero J, Maldonado-Vlaar C. A testosterone metabolite is rewarding to ovariectomized female rats. Behavioral Neurosciences 2005 Oct;119(5):1222-1226.

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- Claude Bernard -

“The joy of discovery is certainly the liveliest that the mind of man can ever feel”

PUBLICATIONS

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